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. 2012 Jun 29;7(6):e40169. doi: 10.1371/journal.pone.0040169

Figure 3. Suppression of cell invasion and metastasis in vitro and in vivo by over-expression of miR-125a.

Figure 3

(A and B) Migration and invasion assays confirmed that the invasive abilities of HepG2 and HCC-LM3 cells were significantly inhibited by ectopic expression of miR-125a. The data presented are the mean of three independent experiments. *P<0.05 VS each control. (C) LM-125a and LM3-NC cells were used for the in vivo metastasis assays. The pictures shown are the representative anatomical photos of livers and lungs from mice injected with LM-125a or LM3-NC cells. (D) The data presented are the incidences of metastasis in both the livers and lungs of mice.