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PfEMP1 architecture of variants up-regulated after HBEC-5i selection. ATS, acidic terminal segment; CIDR, cysteine-rich interdomain region; DBL, Duffy binding-like domain; DC13, domain cassette 13; DC8, domain cassette 8; NTS, N-terminal segment. Pairwise amino acid identities between domains are shown in SI Appendix, Tables S4 and S5.
