Figure 4. Knocking down CK2 inhibited ER stress-induced XBP-1 splicing.

CK2 siRNA decreased ER stress-induced XBP-1 splicing compared with control siRNA. Primary cultured glial cells were transfected with 75 nM siRNA and treated with tunicamycin (Tm: 0.01 µg/mL) for 4 h. A RT-PCR analysis was then performed. n = 3/group. Results are expressed as the means ± S.E.