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. 2012 Jun 29;7(6):e39302. doi: 10.1371/journal.pone.0039302

Figure 6. L-NAME treatment increased doublecortin levels in the rat hippocampus.

Figure 6

L-NAME treatment increased DCX immunoreactivity on Western blots (A) by 2.2-fold (p = 0.02) at day 50 post-seizure (B). By immunohistochemistry, numerous DCX-positive cells were detected in the subgranular zone of the dorsal hippocampus by day 50 post-seizure (C). Quantitatively, L-NAME elicited significant increases (1.5-fold, p = 0.01) in the number of DCX-positive cells (D). Abbreviations: gcl, granule cell layer.