Skip to main content
. 2012 Jun 29;7(6):e38224. doi: 10.1371/journal.pone.0038224

Table 1. Characteristics of the study population.

female male p NGTa IFGb pc IGTd pc IFG+IGTe pc
959 483 1046 142 140 114
age (years) 39.2±12.9 40.2±13.4 0.26 37.5±12.4 43.4±13.0 <0.0001 42.1±13.2 <0.0001 49.7±13.3 <0.0001
BMI (kg/m2) 28.7±8.1 28.1±7.3 0.66 27.2±6.8 32.7±10.8 <0.0001 29.7±7.3 <0.0001 33.8±9.6 <0.0001
family history of diabetes 48.5% 49.0% 0.77 45.8% 58.5% 0.006 60.4% 0.002 52.7% 0.19
systolic blood pressure (mmHg) 121±17 126±16 <0.0001 119±15 128±16 <0.0001 128±16 <0.0001 134.0±18.9 <0.0001
diastolic blood pressure (mmHg) 75±11 77±11 0.07 74±10 78±11 0.002 79±12 <0.0001 81.6±10.5 <0.0001
Fasting glucose (mmol/l) 5.1±0.5 5.2±0.6 0.001 4.9±0.4 5.9±0.3 <0.0001 5.1±0.3 <0.0001 6.1±0.3 <0.0001
2-hour glucose (mmol/l) 6.4±1.6 6.1±1.7 0.001 5.6±1.1 6.2±1.0 <0.0001 8.7±0.8 <0.0001 9.2±1.0 <0.0001
Fasting insulin (pmol/l) 64±54 58±47 0.005 54±43 83±72 <0.0001 71±52 <0.0001 102.4±64.0 <0.0001
2-hour insulin (pmol/l) 453±463 376±412 <0.0001 330±299 424±345 <0.0001 745±580 <0.0001 928±835 <0.0001
HOMA-ß (AU) 139±139 117±86 0.001 131±134 117±104 0.015 151±103 0.004 133±76 0.20
HOMA-IR (AU) 2.5±2.2 2.3±2.1 0.001 2.0±1.6 3.6±3.2 <0.0001 2.7±2.0 <0.0001 4.6±3.1 <0.0001
TG (mmol/l) 1.2±0.8 1.9±2.8 <0.0001 1.3±1.7 1.5±1.7 0.004 1.8±2.1 <0.0001 1.8±1.4 <0.0001
Cholesterin (mmol/l) 5.0±0.9 5.0±1.1 0.45 5.0±1.0 5.0±0.9 0.89 5.2±1.0 0.022 5.1±0.9 0.044
HDL (mmol/l) 1.5±0.4 1.2±0.3 <0.0001 1.4±0.4 1.3±0.3 0.001 1.4±0.3 0.008 1.3±0.3 0.001
LDL (mmol/l) 3.0±0.8 3.2±0.8 0.0003 3.0±0.8 3.1±0.8 0.24 3.2±0.8 0.006 3.2±0.8 0.020
lipid lowering therapy 4.3% 2.4% 0.0007 1.1% 4.9% 0.003 5.7% 0.001 7.0% 0.0002
antihypertensive therapy 9.5% 7.9% 0.12 4.8% 12.7% 0.0007 10.7% 0.009 27.2% <0.0001

Data are means ± standard deviations.

a

normal glucose tolerance.

b

isolated impaired fasting glycemia.

c

as compared to normal glucose tolerance.

d

isolated impaired glucose tolerance.

e

concomitant impaired fasting glycemia and impaired glucose tolerance.