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. 2012 Jun 29;7(6):e38870. doi: 10.1371/journal.pone.0038870

Table 2. The top ten GeneGo pathways/processes and GO processes resulting from genes identified via literature review.

Ranking GeneGo Pathways
1 DNA damage_Role of Brca1 and Brca2 in DNA repair
2 DNA damage_ATM/ATR regulation of G1/S checkpoint
3 DNA damage_NHEJ mechanisms of DSBs repair
4 DNA damage_Brca1 as a transcription regulator
5 Signal transduction_AKT signaling
6 Some pathways of EMT in cancer cells
7 Apoptosis and survival_Ceramides signaling pathway
8 Signal transduction_PTEN pathway
9 Transcription_P53 signaling pathway
10 DNA damage_ATM/ATR regulation of G2/M checkpoint
Ranking GeneGo Processes
1 DNA damage_Checkpoint
2 DNA damage_DBS repair
3 Cell cycle_G1-S Growth factor regulation
4 DNA damage_BER-NER repair
5 Cell cycle_Meiosis
6 DNA damage_Core
7 Apoptosis_Apoptotic nucleus
8 Cell cycle_G1-S Interleukin regulation
9 Development_EMT_Regulation of epithelial-to-mesenchymal transition
10 Cell cycle_S phase
Ranking GO Processes
1 Cellular response to stimulus
2 Cellular response to stress
3 Response to stress
4 Regulation of programmed cell death
5 Regulation of cell death
6 Regulation of apoptosis
7 Response to DNA damage stimulus
8 Response to stimulus
9 DNA repair
10 Response to organic substance