Table 1. Biological and clinical characteristic of patients.
Patients | 71 |
Median age, years (range) | 64 (40–95) |
Male/Female | 41/30 |
Wbc count,/mm3 (range) | 61209 (8300–198200) |
Lymphocytes, % (range) | 80 (41–97) |
Mutated1 | 28 |
ZAP70 positive2 | 30 |
CD38 positive3 | 20 |
Karyotype (N4/13q−/12+/11q−/17p-) | 12/18/3/7/4 |
“Mutated” was defined as having a frequency of mutations greater than 2% from germline VH sequence.
As determined by cytofluorymetric analysis (cut-off: 20%).
As determined by cytofluorymetric analysis (cut-off: 30%).
N = normal karyotype.