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. 2012 Jun 29;7(6):e39893. doi: 10.1371/journal.pone.0039893

Figure 6. Survival after myocardial infarction.

Figure 6

Kaplan-Meier survival analysis of rats with acute myocardial infarction. *p<0.05 vs. LETO. 4-PBA  =  pretreatment with 4-PBA at dose of 40 mg/kg/day; 4-PBA80 =  pretreatment with 4-PBA at a dose of 80 mg/kg/day; Cyclosporine A  =  pretreatment with cyclosporine A at dose of 20 mg/kg/day; TUDCA =  pretreatment with sodium tauroursodeoxycholic acid (100 mg/kg/day). All agents were administered intraperitoneally for 7 days before infarct experiments. Experiments using TUDCA and a higher dose of 4-PBA (i.e., 4-PBA80 group) were additionally performed as post-hoc experiments.