Table 2. Summary data from pressure-volume relationships.
| LETO | OLETF | OLETF+4-PBA | |
| (n = 5) | (n = 6) | (n = 6) | |
| Body weight (g) | 533±17 | 605±26* | 624±14* |
| Heart weight (g) | 1.53±0.05 | 1.83±0.11* | 1.74±0.02 |
| Heart weight/Body weight (%) | 0.29±0.01 | 0.30±0.01 | 0.28±0.01 |
| HR (beats/min) | 391±8 | 341±16* | 327±9* |
| LVESP (mmHg) | 100.5±1.6 | 133.2±3.2* | 136.2±9.1* |
| LVEDP (mmHg) | 10.4±3.0 | 5.5±1.8 | 4.6±2.3 |
| LVEDV (ml) | 0.14±0.012 | 0.17±0.013 | 0.18±0.019 |
| LVESV (ml) | 0.06±0.005 | 0.09±0.012 | 0.07±0.013 |
| SV (ml) | 0.08±0.009 | 0.09±0.017 | 0.11±0.008* |
| LVEF (%) | 56.3±3.4 | 50.8±4.2 | 62.4±3.8 |
| CO (ml/min) | 30.6±3.1 | 29.0±2.4 | 37.3±3.3 |
| LV dP/dtmax (mmHg/s) | 6665±805 | 7469±356 | 8660±555 |
| LV dP/dtmin (mmHg/s) | −6824±545 | −8633±561* | −9428±276* |
| tau (ms) | 10.2±1.1 | 9.7±1.7 | 10.3±1.2 |
| Ees (mmHg/ml) | 3392±567 | 3397±418 | 2748±356 |
| Eed (mmHg/ml) | 20.2±5.6 | 53.9±5.2* | 24.2±6.0 |
| Vp (ml) | 0.19±0.02 | 0.20±0.01 | 0.20±0.01 |
Values are means±SEM. *P<0.05 vs. LETO. HR = heart rate; LVESP = left ventricular end-systolic pressure; LVEDP = left ventricular end-diastolic pressure; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; LVEF = left ventricular ejection fraction; CO = cardiac output; LV dP/dtmax and dP/dtmin = left ventricular maximal slope of the systolic pressure increment and the diastolic pressure decrement, respectively; tau = time constant of left ventricular pressure decay; Ees = end-systolic elastance of left ventricle; Eed = end-diastolic elastance of left ventricle; Vp = parallel conductance volume.