Table 1. Characteristics of Profiling Cohorts (Mean±Se).
| PARAMETER | DM2 (N = 13) | CONTROLS (N = 13) | p |
| AGE (years) | 56.9±1.9 | 49.3±2.5 | ns |
| SEX (f/m) | 5/8 | 5/8 | ns |
| STRENGHT (biopsied muscle) (MRC scale) | 4.5±0.1 | 4.9±0.04 | ns |
| STRENGHT (Megascore on 15 muscles, MRC scale) | 137.4±9.1 | 145.6±6.8 | ns |
| MYOTONIA (%) | 85 | 0 | <0.0001 |
| GLUCOSE (mg/dl) (n.v.70–110) | 101.4±16.0 | 86.0±8.5 | ns |
| DIABETES MELLITUS (%) | 18 | 0 | ns |
| CPK (IU/l) (n.v. m<190, f<167) | 292.7±3.5 | 236.4±67.1 | ns |
| FT3 (pg/ml) (n.v. 1.5–4.1) | 3.0±3.1 | 1.7±0.5 | ns |
| FT4 (ng/dl) (n.v. 0.8–1.9) | 1.3±0.3 | 1.2±0.3 | ns |
| TSH (mIU/ml) (n.v. 0.4–4.0) | 1.0±0.2 | 0.7±0.2 | ns |
| ECG-QRS duration (msec) (n.v. 60–100) | 94.3±16.4 | 85.9±12.1 | ns |
| EF (%) (n.v.>50) | 54.5±9.7 | 64.0±19.3 | ns |
| ICM (%) | 9 | 0 | ns |
| SERIC β-GLOBULIN (%) | 12.3±1.7 | 14.1±2.0 | ns |
| CATARACT (%) | 70 | 0 | <0.0005 |
Abbreviations: MRC scale = Medical Research Council scale (0–5 grade); CPK = Creatine PhosphoKinase; FT3 = free-triiodothyronine; FT4 = free-thyroxine; TSH = thyroid stimulating hormone; ECG = electrocardiogram; QRS duration = QRS complex of ECG corresponds to the depolarization of the right and left ventricles of the human heart; EF = ejection fraction; ICM = ischemic cardiomyopathy.