Figure 3. CD40/CD154 pathway-sparing regimens are well tolerated.

Individual recipient weights over the experimental course are depicted here. Percent change is calculated based on weight on day of transplant. While some weight loss in the immediate post-transplant period was common, most recipients successfully stabilized around post-transplant day 25. Late weight loss was uncommon, affecting only a single cohort 3 recipient (Alef-3), and did not result in early experimental termination. Dotted line represents weight baseline at transplant. POD – post-operative day.