Table 2.
Baseline characteristics of study participants (n= 16445) by exposure group
| E+P MHT (n=4712) |
E+P unexposed (n=8070) |
E-only MHT (n=1208) |
E-only unexposed (n=2055) |
|
|---|---|---|---|---|
| Age at study entry, mean±SD (95% CI), years | 58.2±6.3 (50.0–79.8) | 58.9±6.2 (50.0–79.7) | 59.2±6.9 (50.0–79.6) | 59.7±6.7 (50.0–79.8) |
| Age group at study entry | ||||
| 50–59 (%) | 3219 (68.3) | 4978 (61.7) | 736 (60.9) | 1156 (56.3) |
| 60–69 (%) | 1202 (25.5) | 2545 (31.5) | 362 (30.0) | 707 (34.4) |
| 70–79 (%) | 291 (6.2) | 547 (6.8) | 110 (9.1) | 192 (9.3) |
| Smoking | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Obesity | 2 (0.04) | 2 (0.03) | 1 (0.08) | 1 (0.01) |
| Hypertension (%) | 503 (10.6) | 529 (6.6) | 157 (13.0) | 143 (7.0) |
| Hypercholesterolemia (%) | 194 (4.1) | 126 (1.6) | 52 (4.3) | 41 (2.0) |
| Statin use (%) | 329 (6.9) | 294 (3.6) | 101 (8.4) | 96 (4.7) |
| Aspirin use (%) | 262 (5.5) | 313 (3.9) | 90 (7.4) | 79 (3.8) |
| Treated for diabetes (%) | 373 (7.9) | 662 (8.2) | 137 (11.3) | 178 (8.7) |
| History of fracture ≥age 55 (%) | 42 (0.89) | 59 (0.73) | 12 (0.99) | 21 (1.0) |
| Exposure in days median (95% CI) | 211 (56–3569) | 0 (0–1974) | 276 (56–3760) | 0 (0–1966) |