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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2012 Apr 21;130(1):195–204.e9. doi: 10.1016/j.jaci.2012.02.042

FIG 3. TLR8 agonists are refractory to inhibitory adenosine/cAMP and associated with lesser cAMP accumulation in newborn Mos.

FIG 3

A, Monocytes, to which adenosine (10 μM) or saline (Sal) added prior to stimulation with agonists (50 μM) for 2 hrs (representative of 3-6 experiments). B, % cytokine. C, cAMP concentrations in agonist treated monocytes. D, 30 min db-cAMP (10 μM) treated monocytes, 4 hr stimulation. n =3–6; * P < 0.05, ** P < 0.01.