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. Author manuscript; available in PMC: 2013 Jul 11.
Published in final edited form as: Chem Rev. 2012 Mar 16;112(7):4221–4245. doi: 10.1021/cr100351g

Figure 20.

Figure 20

Fidelity experiments with β-pyrene nucleoside triphosphate (dPTP) showed that the Klenow fragment of E. coli DNA polymerase I preferentially inserted dPTP opposite an abasic site on the template strand, compared to the natural nucleotides. Reproduced with permission from Ref. 86. Copyright 1999 Nature Publishing Group.