Comparison of repeat biopsy outcome in vitamin D3-supplemented subjects. Estimates (in percent) of progression (A) and improvement (B) for all analyzable subjects (n = 44, y-axis) and by entry values of serum 25(OH)D (<20 ng/ml vs. >20 ng/ml, x-axis) are shown. Bars are exact 95% confidence intervals (CI). Progression (CI in parentheses): 34% of all subjects (0.20, 0.50); 45% of vitamin D-deficient subjects (0.17, 0.77); and 30% of nondeficient subjects (0.16, 0.49). Improvement (CI in parentheses): 55% of all subjects (0.39, 0.70); 36% of vitamin D-deficient subjects (0.11, 0.69); and 61% of nondeficient subjects (0.42, 0.77).