Table 4.
The association between metabolic health (defined by blood pressure, HDL cholesterol, diabetes, CRP), waist, and mortalitya
| Cases/n | Age- and sex-adjusted HR (95% CI) | Fully adjusted HR (95% CI)b | |
|---|---|---|---|
| CVD death | |||
| Metabolically healthy, normal waist | 83/7129 | 1.00 (referent) | 1.00 |
| Metabolically unhealthy, normal waist | 280/7535 | 1.78 (1.39–2.28) | 1.61 (1.26–2.08) |
| Metabolically healthy, large waist | 18/1529 | 0.81 (0.49–1.35) | 0.82 (0.49–1.40) |
| Metabolically unhealthy, large waist | 224/6019 | 1.78 (1.38–2.30) | 1.57 (1.15–2.15) |
| P trend | <0.001 | <0.001 | |
| All-cause death | |||
| Metabolically healthy, normal waist | 302/7129 | 1.00 (referent) | 1.00 |
| Metabolically unhealthy, normal waist | 850/7535 | 1.59 (1.39–1.81) | 1.51 (1.32–1.73) |
| Metabolically healthy, large waist | 66/1529 | 0.84 (0.64–1.09) | 1.03 (0.78–1.37) |
| Metabolically unhealthy, large waist | 651/6019 | 1.51 (1.31–1.73) | 1.84 (1.54–2.18) |
| P trend | <0.001 | <0.001 |
Sample contains participants without history of CVD at baseline (n = 22,203).
a
Large waist defined as greater than 102 cm in men and greater than 88 cm in women.
b
Contains adjustment for age, sex, smoking, physical activity, socioeconomic group, and BMI.