Table 3.
Characteristics of the analytic sample by individual components comprising MetSa
| Outcome | Number of MetS criteria met |
P value for trendb | |||||
|---|---|---|---|---|---|---|---|
| Zero (n = 877) | One (n = 680) | Two (n = 463) | Three (n = 313) | Four (n = 154) | Five (n = 51) | ||
| Sociodemographic | |||||||
| Age at baseline (yr) | 45.4 (45.3, 45.6) | 45.8 (45.6, 46.0) | 45.8 (45.6, 46.0) | 46.0 (45.7, 46.3) | 45.7 (45.3, 46.2) | 46.3 (45.5, 47.1) | 0.002 |
| BMI (kg/m2) | 22.8 (22.6, 23.0) | 26.2 (25.8, 26.6) | 31.2 (30.6, 31.8) | 33.1 (32.4, 33.9) | 35.0 (34.0, 36.0) | 36.4 (34.7, 38.2) | |
| Ethnicity (%) | |||||||
| White | 54.5 (478) | 47.2 (321) | 36.5 (169) | 40.9 (128) | 46.1 (71) | 41.2 (21) | <0.001 |
| Black | 14.6 (128) | 29.3 (199) | 43.2 (200) | 38.7 (121) | 34.4 (53) | 37.3 (19) | |
| Chinese | 10.9 (96) | 6.8 (46) | 4.8 (22) | 3.8 (12) | 3.9 (6) | 5.9 (3) | |
| Hispanic | 5.2 (46) | 7.8 (53) | 8.9 (41) | 9.9 (31) | 11.7 (18) | 13.7 (7) | |
| Japanese | 14.7 (129) | 9.0 (61) | 6.7 (31) | 6.7 (21) | 3.9 (6) | 2.0 (1) | |
| Education beyond high school (%) | 81.2 (708) | 75.8 (510) | 69.0 (316) | 72.6 (223) | 61.7 (95) | 60.0 (30) | <0.001 |
| Physical activity score | 8.1 (7.9, 8.2) | 7.4 (7.3, 7.5) | 7.1 (6.9, 7.2) | 7.0 (6.8, 7.2) | 7.0 (6.7, 7.2) | 6.7 (6.3, 7.2) | <0.001 |
| Very hard to paying for basics (%) | 5.8 (51) | 9.2 (62) | 10.8 (50) | 12.9 (40) | 15.6 (24) | 13.7 (7) | <0.001 |
| Current smoking (%) | 10.9 (95) | 17.2 (116) | 19.1 (88) | 20.1 (62) | 23.7 (36) | 29.4 (15) | <0.001 |
| CES-D indicating depression (%) | 18.9 (166) | 23.2 (158) | 29.4 (136) | 29.7 (93) | 30.5 (47) | 25.5 (13) | <0.001 |
| Difficulty sleeping past 2 wk (%) | 38.9 (341) | 44.1 (298) | 43.9 (202) | 48.2 (151) | 44.2 (68) | 45.1 (23) | 0.005 |
| Reproductive | |||||||
| Premenopausal status (%) | 58.0 (498) | 54.4 (361) | 52.1 (237) | 52.8 (161) | 51.0 (78) | 30.0 (15) | <0.001 |
| SHBG (nm/liter) | 47.5 (45.8, 49.3) | 40.9 (39.2, 42.7) | 34.2 (32.3, 36.1) | 31.5 (29.8, 33.3) | 26.6 (24.4, 29.1) | 26.8 (22.9, 31.3) | <0.001 |
| DHEAS (μg/dl) | 121.9 (117.2, 126.7) | 106.5 (100.8, 112.6) | 96.9 (91.0, 103.3) | 99.1 (92.2, 106.5) | 90.4 (79.6, 102.6) | 83.8 (66.5, 105.6) | <0.001 |
| Estradiol (pg/ml) | 62.1 (59.0, 65.4) | 53.9 (50.9, 57.1) | 56.4 (52.7, 60.3) | 48.0 (44.2, 52.0) | 48.1 (43.7, 52.9) | 49.0 (40.2, 59.6) | <0.001 |
| TSH (μIU/ml) | 1.9 (1.8, 1.9) | 1.8 (1.7, 1.9) | 1.9 (1.8, 1.9) | 1.8 (1.7, 1.9) | 1.9 (1.8, 2.1) | 1.9 (1.7, 2.1) | 0.723 |
| T/DHEAS ratio | 325.3 (312.6, 338.5) | 368.6 (349.6, 388.7) | 414.9 (389.3, 442.2) | 449.9 (417.5, 484.8) | 506.0 (449.6, 569.5) | 584.2 (451.3, 756.2) | <0.001 |
| FAI | 2.9 (2.8, 3.0) | 3.3 (3.1, 3.5) | 4.1 (3.8, 4.4) | 4.9 (4.5, 5.3) | 6.0 (5.3, 6.7) | 6.3 (5.2, 7.7) | <0.001 |
| T, ng/dl | 39.6 (38.4, 41.0) | 39.3 (37.7, 40.9) | 40.2 (38.4, 42.2) | 44.6 (41.9, 47.4) | 45.7 (41.6, 50.3) | 49.0 (43.1, 55.5) | <0.001 |
CES-D, Center for Epidemiologic Studies Depression Scale.
a
Values in table geometric mean (95% CI) for continuous variables or percent (n) for categorical variables.
b
Cochran-Armitage test for trend was used for trend for categorical variables; linear test for trend was used for continuous variables; P value for race is from a χ 2 but not a test for trend.