Table 2.

Metabolic characteristics by type of MC4R mutation among 847 men and women 1 yr after RYGB

Variable	Type of MC4R mutation
	None	Single-copy pathogenic	P vs. none	Single-copy nonpathogenic	P vs. none
LDL cholesterol (mg/dl) (sd)	86.9 (28.0)	94.8 (16.7)	0.16	86.0 (28.8)	0.65
HDL cholesterol (mg/dl) (sd)	54.8 (14.3)	57.7 (11.3)	0.38	58.5 (13.7)	0.14
Glucose (mg/dl) (sd)	93.7 (25.3)	96.2 (19.0)	0.35	91.2 (20.8)	0.37
Insulin (μIU/ml) (sd)	7.2 (6.0)	7.3 (4.0)	0.57	5.4 (2.3)	0.32
HbA1c (sd)	5.6 (0.73)	5.5 (0.65)	0.72	5.5 (0.53)	0.41