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. 2012 Mar 30;97(6):E888–E897. doi: 10.1210/jc.2011-3073

Fig. 4.

Fig. 4.

Effect of progesterone on TGFβ-induced increases in MMP2 (A) and MMP11 (B) mRNA in HESC. Cells were treated with vehicle [control (Ctl)], progesterone (P, 10−9 m), TGFβ1 (5 ng/ml), or progesterone (10−10 to 10−7 m) plus TGFβ1 for 48 h. Thereafter, mRNA levels were quantified. Data for Ctl, P, TGFβ1, and P (10−9) plus TGFβ1 represent mean ± sem of results from nine experiments conducted with nine cell preps. The inhibitory dose-response curve with P (10−10 to 10−7 m) represent mean ± sem of four samples in each group. **, P < 0.01 compared with control; *, P < 0.01 compared with TGFβ1 alone, ANOVA.