Table 1.

Clinical features of tissue samples used for methylation profiling

	Benign tumor	Primary tumor	Metastatic tumor
Number of samples	48	8	12
Age (yr), mean ± sem	48.9 ± 1.0	42.3 ± 5.3	57.2 ± 4.8
Gender (women/men)	35/13	5/3	11/1
Type of tumor	48 primary	8 primary	7 locoregional recurrence, 2 liver metastases, 2 lung metastases, 1 abdominal wall metastasis
Syndrome
Hypercortisolism	16	6	7
Hyperaldosteronism	16	0	0
Nonfunctioning	16	2	5