Table 3.
Multivariate Cox proportional hazards regression for the effect of gender on disease-specific survival using an initial age cutoff of 55 yr within each stage while adjusting for age, with P value for gender difference shown
Population | Patients, n | Deaths, n | 15-yr survival (%) | 95% CI for 15-yr survival | HR | 95% CI for HR | P value |
---|---|---|---|---|---|---|---|
All stages | |||||||
Males | 953 | 30 | 91 | 0.86–0.94 | 1.00 | ||
Females | 2619 | 34 | 96 | 0.93–0.98 | 0.48 | 0.29–0.79 | 0.004 |
Stages I and II | |||||||
Males | 603 | 5 | 98 | 0.94–0.99 | 1.00 | ||
Females | 2125 | 2 | 100 | 0.99–1.00 | 0.10 | 0.02–0.51 | 0.006 |
Stage III | |||||||
Males | 296 | 10 | 86 | 0.73–0.93 | 1.00 | ||
Females | 428 | 16 | 87 | 0.75–0.94 | 0.95 | 0.43–2.11 | 0.908 |
Stage IV | |||||||
Males | 51 | 15 | 50 | 0.26–0.70 | 1.00 | ||
Females | 65 | 16 | 62 | 0.44–0.76 | 0.84 | 0.41–1.71 | 0.632 |
Stages I and II patients were combined into one low-risk group because they accounted for very few deaths. HR = 1.0 for <55 yr.