Table 4.
Associations of TSH category and TPOAb positivity with transitions in thyroid status at 2 yr in individuals with subclinical hypothyroidism at baseline
| Risk factor | Euthyroid (n = 128) | Overt hypothyroid (n = 8) | Started l-T4 (n = 25) | P value |
|---|---|---|---|---|
| TSH at baseline | <0.0001 | |||
| 4.5–6.9 mU/liter | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |
| 7.0–9.9 mU/liter | 0.16 (0.07–0.36) | 0.75 (0.08–7.47) | 1.31 (0.45–3.82) | |
| 10–19.9 mU/liter | 0.18 (0.05–0.63) | 7.11 (1.41–35.9) | 4.56 (1.63–1.28) | |
| TPOAb positive | 0.24 (0.14–0.43) | 0.71 (0.16–3.18) | 0.85 (0.35–2.04) | <0.0001 |
Reference group is persistent subclinical hypothyroidism (n = 208). Statistically significant comparisons are indicated in bold.