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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Cleft Palate Craniofac J. 2011 Nov 10;50(1):96–103. doi: 10.1597/11-132

Figure 1.

Figure 1

Testing for main effects (G) of individual SNPs (haplotypes) of FGFR2 and gene–environment interaction (GxE) for two common maternal exposures in 221CL/P case–parent trios from Asian populations. Triangles represent the 2 df test of G and GxE interaction, squares represent the 1 df test of G x E only. Haplotypes of 2- and 3-SNPs are connected by solid lines for 2dftest and dotted lines for 1 df test (only nominally significant haplotypes are shown here). rs2912762*: The distance between rs3135761 and rs2912762 were drawn for clarity (true distance between these two SNPs is 199 base pairs).