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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Cleft Palate Craniofac J. 2011 Nov 10;50(1):96–103. doi: 10.1597/11-132

Figure 3.

Figure 3

Significance [as –log10(p)] from 4df LRT for Cordell's test of GxG interaction between markers in FGF18 and FGF9 plotted against the physical position in FGF9. SNP (rs2043278) in FGF18 is an intronic marker located at 170,815,212 (Build 36) and showed moderately significant p-values for 11 different SNPs in FGF9 (solid circles), most of which were located in the 3'UTR (some as far as 500 Kb away from the coding region of FGF9). Five additional SNPs in FGF18 also yielded strong evidence of GxG interaction with SNPs in the intergenic region 3' of the FGF9 coding region (open symbols).