Table 1.
Baseline Characteristics by Incident Fracture Status
| Characteristic | All (n = 5893) | Hip | Major Osteoporotic | ||
|---|---|---|---|---|---|
|
| |||||
| No Fracture (n = 5737) | Fracture (n = 156) | No Fracture (n = 5558) | Fracture (n = 335) | ||
| Age, means (SD), y | 73.62 (5.86) | 73.5 (5.81) | 78.12 (6.18)c | 73.42 (5.79) | 76.87 (6.16)c |
| 64 to 69 | 1752 (29.73) | 1738 (30.29) | 14 (8.97)c | 1707 (30.71) | 45 (13.43)c |
| 70 to 74 | 1681 (28.53) | 1654 (28.83) | 27 (17.31) | 1607 (28.91) | 74 (22.09) |
| 75 to 79 | 1421 (24.11) | 1372 (23.91) | 49 (31.41) | 1323 (23.80) | 98 (29.25) |
| ≥80 | 1039 (17.63) | 973 (16.96) | 66 (42.31) | 921 (16.57) | 118 (35.22) |
| Race/ethnicity | |||||
| White | 5269 (89.41) | 5122 (89.28) | 147 (94.23) | 4958 (89.20) | 311 (92.84) |
| Black | 242 (4.11) | 240 (4.18) | 2 (1.28) | 236 (4.25) | 6 (1.79) |
| Asian | 188 (3.19) | 187 (3.26) | 1 (0.64) | 179 (3.22) | 9 (2.69) |
| Hispanic | 124 (2.10) | 121 (2.11) | 3 (1.92) | 118 (2.12) | 6 (1.79) |
| Other/unknown | 70 (1.19) | 67 (1.17) | 3 (1.92) | 67 (1.21) | 3 (0.90) |
| Body mass index, mean (SD), kg/m2a | 27.4 (3.82) | 27.43 (3.81) | 26.53 (3.83)c | 27.44 (3.79) | 26.9 (4.14)c |
| <25 | 1570 (26.64) | 1513 (26.37) | 57 (36.54)c | 1447 (26.03) | 123 (36.72)c |
| 25 to <30 | 3029 (51.40) | 2957 (51.54) | 72 (46.15) | 2886 (51.93) | 143 (42.69) |
| ≥30 | 1294 (21.96) | 1267 (22.08) | 27 (17.31) | 1225 (22.04) | 69 (20.60) |
| Fracture history (>45 years) | 1247 (21.16) | 1198 (20.89) | 49 (31.41)c | 1134 (20.41) | 113 (33.73)c |
| Parental history of hip fracture | 744 (16.60) | 725 (16.59) | 19 (16.81) | 698 (16.45) | 46 (19.09) |
| Current cigarette smoker | 205 (3.48) | 195 (3.40) | 10 (6.41)c | 191 (3.44) | 14 (4.18) |
| Oral corticosteroid use in the past 30 days | 104 (1.84) | 104 (1.89) | 0 | 102 (1.91) | 2 (0.62) |
| History of rheumatoid arthritis | 304 (5.16) | 292 (5.09) | 12 (7.69) | 279 (5.02) | 25 (7.46)c |
| Have secondary osteoporosisb | 172 (3.04) | 166 (3.01) | 6 (4.00) | 161 (3.02) | 11 (3.42) |
| ≥3 alcoholic drinks/day on average | 237 (4.03) | 233 (4.07) | 4 (2.56) | 230 (4.14) | 7 (2.10) |
| Femoral Neck BMD, mean (SD), g/cm2 | 0.79 (0.13) | 0.79 (0.13) | 0.66 (0.11)c | 0.79 (0.13) | 0.71 (0.12)c |
| Femoral Neck BMD T-score, mean (SD) | -1.12 (0.91) | -1.09 (0.90) | -1.97 (0.80)c | -1.09 (0.90) | -1.64 (0.90)c |
| Normal (>-1.0) | 2459 (41.73) | 2444 (42.60) | 15 (9.68)c | 2383 (42.88) | 76 (22.75)c |
| Low bone mass (between -1.0 and -2.5) | 3151 (53.48) | 3055 (53.25) | 96 (61.94) | 2951 (53.09) | 200 (59.88) |
| Osteoporosis (≤-2.5) | 282 (4.79) | 238 (4.15) | 44 (28.39) | 224 (4.03) | 58 (17.37) |
| Femoral Neck BMD Z-score, mean (SD) | 0.21 (0.92) | 0.23 (0.92) | -0.52 (0.82)c | 0.23 (0.92) | -0.23 (0.92)c |
Values shown as No. (%) unless otherwise indicated.P values for continuous variables with normal distributions are from a t-test, with skewed distributions from a Wilcoxon rank-sum test. P values for categorical variables from a chi-square test.
a
BMI values for 2 participants with missing data were set to the median value, 26.9 kg/m2.
b
Secondary osteoporosis is defined as having a history of hyperthyroidism or taking insulin.
c
P value compared to non fracture of that type < .05