Table 4.
Detected masses-rt pairs contributing to the separation of the ethanol treated rat (4 weeks) urine samples from the corresponding controls (+ESI dataset). The trend is referred to ethanol treated animals. (Metabolites in Bold = comparison with authentic standards, metabolites in italic = by comparison with databases).
| m/z | Rt (min) | Fold Change | p-value | Putative ID |
|---|---|---|---|---|
| 271.9967 | 0.98 | 21 | 0.0005 | |
| 148.0124 | 1.10 | 21 | 0.001 | |
| 201.0507 | 1.22 | 28 | 0.001 | |
| 240.0916 | 1.67 | NA | 0.001 | |
| 501.0758 | 0.0001 | |||
| 141.0234 | 1.60 | NA | 0.006 | |
| 159.0321 | 0.006 | |||
| 723.1499 | 1.69 | NA | 0.0007 | |
| 209.1288 | 1.81 | 82 | 0.0009 | |
| 199.1077 | 2.28 | NA | <10e-4 | |
| 453.1954 | 2.56 | 25 | 0.05 | |
| 206.0445 | 2.70 | 1.9 | 0.02 | Xanthurenic acid |
| 483.3342 | 10.65 | 0.5 | 0.002 | |
| 397.2957 | 11.01 | 0.04 | 0.0002 | |
| 227.1265 | 11.02 | 0.43 | 0.0002 | |
| 419.2775 | 0.43 | 0.0002 | ||
| 441.3204 | 0.44 | 0.0002 | ||
| 485.3463 | 0.42 | 0.0002 | ||
| 502.3760 | 0.43 | 0.0002 |
Fold change denotes the ratio between the average signal from samples from treated animals versus the average signal from samples from control animals. Values >1 denote increase in treated animals. Values <1 denote decrease in treated animals. NA signifies that the ion was not detected in the control samples. Zero value signifies that the ion was not detected in treated samples