Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A2A receptor activation suppresses tumor necrosis factor-α (TNF-α), interleukin (IL)-12, and nitric oxide (NO) production and augments IL-10 production by classically activated macrophages. A2B receptor activation augments arginase-1, tissue inhibitor of metalloproteinases-1 (TIMP-1), and mgl-1 expression in alternatively activated macrophages. IL-4R indicates IL-4 receptor; mgl-1, macrophage galactose-type C-type lectin; TLR4, toll-like receptor 4.
