Table 5.

Expectancy-related differences in pain report-related responses during remifentanil administration

Regions	x	y	z	No. of voxels	Volume (mm3)	−log(Min. p value)
Expectancy-related increases associated with pain relief (Open > Hidden)
Left hippocampus (CA)	−34	−22	−18	22	176	8.77
Inferior temporal gyrus	44	−38	−10	239	1912	13.58
Right midorbital gyrus	16	58	−6	398	3184	13.85
Left amygdala	−20	−8	−12	53	424	8.16
Right subgenual anterior cingulate cortex	4	14	−10	378	3024	11.03
Left middle temporal gyrus	−58	−50	8	344	2752	10.65
Right middle temporal gyrus	66	−26	−4	157	1256	10.81
Right middle temporal gyrus	52	−56	16	290	2320	8.02
Right inferior frontal gyrus, pars opercularis	38	26	20	18	144	10.12
Right superior occipital gyrus	28	−66	30	166	1328	14.47
Right angular gyrus	46	−60	34	75	600	7.93
Left inferior parietal lobule	−48	−50	40	25	200	10.59
Left angular gyrus	−32	−82	48	28	224	8.91
Expectancy-related decreases associated with pain relief (Hidden > Open)
Left amygdale	−14	0	−24	37	296	13.23
Right amygdale	34	12	−22	372	2976	10.16
Right cerebellum III	12	−40	−22	119	952	9.26
Left thalamus	−12	−20	2	237	1896	10.32
Right thalamus	12	−14	4	350	2800	14.82
Left SII/Postcentral gyrus	−50	−20	18	82	656	10.02
Right middle frontal gyrus	26	52	22	95	760	8.85
Left dorsal posterior insula	−36	−20	18	14	112	10.19
Right dorsal posterior insula	48	−16	24	64	512	8.43
Left S1/Postcentral Gyrus (BA3a)	−36	−24	46	43	344	9.94
Left superior parietal lobule	−26	−68	48	33	264	7.74
Right paracentral lobule (BA4a)	4	−30	64	72	576	11.74
Left precuneus (BA3a)	−12	−42	66	60	480	11.56
Right S1/Postcentral gyrus	30	−34	66	148	1184	9.68
Left paracentral lobule (BA4a)	−8	−40	76	8	64	8.07
Right postcentral gyrus (BA4a)	14	−38	76	6	48	8.43