Table 3.
Ventilatory and hemodynamic variables during the two-hour observation period
| H1/DC < 43% | H1/DC ≥43% | |
|---|---|---|
| Number of patients | 57 | 53 |
| Enrollment SAPS II | 56.0 (53.0 to 66.0) | 57.5 (50.0 to 70.0) |
| Enrollment SOFA | 6 (4 to 8) | 7 (5 to 9) |
| H1/DC (%) | 34.1 (28.9 to 38.2) | 53.1 (47.5 to 61.0) † |
| AI (%) | 20.0 (11.1 to 25.5) | 2.8 (0 to 8.9) † |
| FIO2 (%) | 40.0 (39.8 to 50.0) | 49.8 (40 to 57.8) |
| SpO2 (%) | 97.9 (95.8 to 99.0) | 97.4 (95.6 to 98.9) |
| RR (bpm) | 18.7 (16.0 to 22.0) | 17.5 (14.0 to 22.6) |
| MIP (cmH2O) | 10.4 (8.8 to 12.9) | 10.3 (8.4 to 14.7) |
| PeakP (cmH2O) | 25.2 (20.5 to 32.1) | 27.4 (22.5 to 31.3) |
| VT (mL) | 502 (450 to 560) | 470 (410 to 546) |
| PEEP (cmH2O) | 5.0 (4.7 to 5.5) | 5.1 (4.9 to 5.4) |
| HR (bpm) | 89.8 (78.8 to 98.3) | 86.6 (77.0 to 97.0) |
| MAP (mmHg) | 80.3 (71.9 to 97.0) | 78.7 (70.7 to 95.7) |
| Vasoactive agents (%) | 29.8 | 43.4 |
| Continuous sedation (%) | 59.6 | 75.5 |
AI, Asynchrony Index (%); FIO2, inspired O2 concentration; H1/DC, ratio of first harmonic peak amplitude to DC component amplitude (%); HR, heart rate; MAP, mean arterial pressure; MIP, mean inspiratory pressure; PeakP, peak inspiratory pressure; PEEP, positive end expiratory pressure; RR, respiratory rate; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; SpO2, arterial O2 saturation by pulse oximetry; VT, tidal volume. Data shown as median and IQR; † P < 0.01.