Figure 1.

Individual CRP course for a group of patients during the first five ICU days. Dots indicate the individual observed values at the different time points, from day 1 to day 5, and the dashed lines represent the predictions obtained by a linear mixed model for CRP with random intercept and random slope for time. The intercept (α) describes the initial CRP value and the slope (β) describes the CRP rate of change per day for a specific patient (see text for further explanation). CRP, C-reactive protein; ICU, intensive care unit.