Table 2.
Interventions and outcomesa
| All patients | Excluding patients with preoperative CKD | |||||
|---|---|---|---|---|---|---|
| Variables | AKI (n = 9) | No AKI (n = 91) | P value | AKI (n = 5) | No AKI (n = 69) | P value |
| CABG surgery, n (%) | 2 (22.2%) | 17 (18.7%) | 0.68 | 1 (20.0%) | 13 (18.8%) | >0.99 |
| Valve surgery, n (%) | 4 (44.5%) | 46 (50.5%) | >0.99 | 2 (40.0%) | 37 (53.6%) | 0.66 |
| CABG and valve surgery, n (%) | 3 (33.3%) | 21 (23.1%) | 0.68 | 2 (40.0%) | 14 (20.3%) | 0.29 |
| Thoracic aortic surgery, n (%) | 0 (0.0%) | 7 (7.7%) | >0.99 | 0 (0.0%) | 5 (7.3%) | >0.99 |
| Previous cardiothoracic operation, n (%) | 2 (22.2%) | 26 (28.6%) | >0.99 | 1 (20.0%) | 23 (33.3%) | >0.99 |
| Duration of bypass, minutes | 125 (100 to 172) | 119 (91 to 158) | 0.62 | 109 (80 to 146) | 119 (90 to 156) | 0.57 |
| Fluid balanceb, mL | 4,980 (3,000 to 16,200) | 3,100 (1,690 to 4,660) | 0.035 | 4,920 (450 to 16,200) | 3,100 (1,260 to 4,800) | 0.4 |
| Furosemideb, n (%) | 9 (100%) | 84 (92.3%) | 0.39 | 5 (100.0%) | 63 (91.3%) | >0.99 |
| Furosemideb, mg | 130 (60 to 460) | 50 (20 to 90) | 0.003 | 160 (35 to 672) | 45 (20 to 70) | 0.05 |
| Vasopressor useb, n (%) | 7 (77.8%) | 65 (71.4%) | 0.69 | 5 (100.0%) | 49 (71.0%) | 0.32 |
| Inotrope useb, n (%) | 8 (88.9%) | 51 (63.7%) | 0.13 | 4 (80.0%) | 45 (65.2%) | 0.66 |
| Blood transfusionb, n (%) | 8 (88.9%) | 52 (57.1%) | 0.06 | 4 (80.0%) | 39 (56.5%) | 0.39 |
| Blood transfusionb, mL | 1,000 (500 to 6,380) | 500 (0 to 500) | 0.005 | 1,250 (250 to 6,800) | 250 (0 to 500) | 0.048 |
| LOS in hospital, days | 14 (8 to 19) | 9 (7 to 14) | 0.024 | 14 (8 to 19) | 9 (7 to 14) | 0.48 |
| Need for RRT, n (%) | 3 (33.3%) | 2 (2.2%) | 0.005 | 2 (40.0%) | 0 (0.0%) | 0.004 |
| Hospital mortality, n (%) | 3 (33.3%) | 0 (0%) | 0.001 | 1 (20.0%) | 0. (0.0%) | 0.068 |
aAKI, acute kidney injury; CKD, chronic kidney disease; CABG, coronary artery bypass graft; LOS, length of stay; RRT, renal replacement therapy. AKI is defined as Risk, Injury, Failure, Loss, End-stage renal disease classification of AKI (RIFLE) class R or worse including serum creatinine increase and urine output decrease. Data are medians (25th to 75th percentiles) unless otherwise indicated. bIncluding intraoperative and 48-hour postoperative values.