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. 2011 Aug 11;15(4):R194. doi: 10.1186/cc10355

Table 4.

Results of multivariate analysis of risk factors for complicated hospitalization

Without RDW With RDW RDW and abnormal WBC
% from Total Coef. P value Adjusted odds ratio 95% confidence interval Coef. P value Adjusted odds ratio 95% confidence interval Coef. P value Adjusted odds ratio 95% confidence interval
Lower Upper Lower Upper Lower Upper

Prior neurologic damage 19.6 1.7 <0.0001 5.3 3.4 8.2 1.5 <0.0001 4.5 2.9 7.0 1.6 <0.0001 4.7 3.0 7.3
Heart disease 8.8 0.6 0.044 1.9 1.0 3.5
Corticosteroid therapy 11.9 0.7 0.01 2 1.2 3.5
Post chest radiation 4.9 1.4 <0.001 4.1 1.9 8.9 1.1 0.006 3.1 1.4 6.9 1.1 0.007 3.0 1.4 6.8
BUN >10.7 mmol/L 10.2 0.8 0.008 2.2 1.2 3.8 0.8 0.004 2.3 1.3 4.1 0.8 0.004 2.3 1.3 4.1
WBC <4 or >12 × 109/L 54.5 0.6 0.004 1.8 1.2 2.7
RDW ≤14.5% 34.2 1.0 <0.0001 2.9 1.9 4.2
RDW ≤14.5% and WBC = normal 31 <0.0001 Reference
RDW >14.5% and WBC = normal 49 0.5 0.048 1.7 1.0 3.0
RDW >14.5% and WBC = abnormal 20 1.4 <0.0001 4.1 2.6 6.5
Constant -2.084 -1.96 -1.97
Hosmer and Lemeshow Test 0.543 0.344 0.565
Area under curve 0.7376 0.691 0.781 0.743 0.699 0.788 0.755 0.711 0.799

Elevated RDW levels on admission either alone or in combination of abnormal levels of white blood are associated with significant higher rates complicated hospitalization.

BUN, blood urea nitrogen; Coef, coefficient; RDW, red cell width distribution; WBC, white blood cells.