Table 3.
Day 0 | Day 3 | Day 7 | Day 10 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
All | S | NonS | P | All | S | NonS | P | All | S | NonS | P | All | S | NonS | P | |
N | 178 | 93 | 85 | 152 | 89 | 63 | 129 | 80 | 42 | 73 | 38 | 35 | ||||
PaO2 (mmHg) | 97 (71 to 124) | 98 (76 to 120) | 92 (67 to 129) | .50 | 94 (76 to 122) | 98 (79 to 105) | 87 (72 to 117) | .06 | 96 (79 to 115) | 104 (84 to 125) | 81 (73 to 102) | .001 | 96 (73 to 15) | 106 (76 to 118) | 84 (72 to 110) | .06 |
PaCO2 (mmHg) | 44 ± 14 | 43 ± 12 | 46 ± 15 | .22 | 44 ± 13 | 43 ± 13 | 46 ± 13 | .14 | 47 ± 11 | 44 ± 10 | 51 ± 11 | .02 | 47 ± 13 | 42 ± 10 | 52 ± 14 | .001 |
Arterial pH | 7.29 ± 0.1 | 7.31 ± 0.1 | 7.27 ± 0.1 | .007 | 7.34 ± 0.1 a | 7.37 ± 0.1 | 7.29 ± 0.1 c | .004 | 7.36 ± 0.1 a | 7.39 ± 0.1 | 7.33 ± 0.1 | .002 | 7.37 ± 0.1 c | 7.41 ± 0.1 | 7.32 ± 0.1 | .002 |
HCO3 (mEq/L) | 21 ± 5 | 20 ± 6 | 22 ± 5 | .16 | 24 ± 5 b | 24 ± 5 a | 22 ± 5 | .02 | 27 ± 5 a | 27 ± 5 | 28 ± 5 b | .55 | 27 ± 5 c | 27 ± 5 | 28 ± 7 | .75 |
Fluid balance (ml/day) | 785 (130; 1,802) | 715 (98; 1,810) | 1,000 (170; 1,800) | .99 | 1,050 (74; 210) | 695 (-86; 2,025) | 1,350 (505; 2,560) | .02 | 900 (-352;-1,785) | 700 (-470;-1,770) | 1,000 (-172; 1,810) | .75 | 129 b (-673; 1,100) | 0 b (-800; 1,050) | 757 (-450; 1,415) | .07 |
Data are presented as means ± standard deviations, and medians and (IQR)
NonS, Non-survivors. P, Intergroup comparisons (between survivors vs. non-survivors) at each day are shown. S, Survivors.
For intragroup comparisons over time: Days 3, 7 and 10 are compared to Day 0 values, in all patients, in survivors and in non-survivors.
a P < .001; b P < .01; c P < .05