Table 1.
Diabetic | Non-Diabetic | ||||
---|---|---|---|---|---|
IIT (n = 16) |
CIT (n = 17) |
IIT (n = 27) |
CIT (n = 16) |
P | |
Age (years) | 66.1 ± 3.5 | 65.9 ± 2.0 | 49.3 ± 4.5 | 43.4 ± 5.2 | < 0.0001 |
Sex, male: female | 6:10 | 7: 10 | 22:5 | 13:3 | 0.0001 |
BMI | 31.2 ± 1.6 | 33.8 ± 2.6 | 25.1 ± 0.8 | 26.6 ± 1.0 | 0.0003 |
APACHE II score | 28.6 ± 1.9 | 29.4 ± 1.7 | 22.3 ± 1.6 | 24.1 ± 2.0 | 0.001 |
Blood glucose (mmol/L) | 15.0 ± 1.1 | 13.4 ± 0.9 | 11.1 ± 0.7 | 10.0 ± 0.4 | < .0001 |
Creatinine (μmol/l) | 178 ± 31 | 222 ± 47 | 119 ± 20 | 144 ± 41 | 0.14 |
Creatinine clearance (ml/min) | 55 ± 10 | 52 ± 9 | 90 ± 9 | 95 ± 15 | 0.007 |
Admission category | |||||
Medical | 16 | 16 | 21 | 14 | 0.15 |
Surgical | 0 | 1 | 6 | 2 | 0.15 |
SOFA score (Day 1) | 9.3 ± 0.7 | 10.9 ± 0.8 | 8.3 ± 0.6 | 10.0 ± 0.7 | 0.11 |
SOFA score (Day 3) SEPSIS |
7.4 ± 3.0 | 8.6 ± 3.7 | 7.0 ± 4.0 | 8.9 ± 2.6 | 0.25 |
ICU acquired sepsis | 9 | 7 | 11 | 8 | 0.89 |
Length of hospital stay (days) | 64.4 ± 14.4 | 42.6 ± 8.8 | 48.4 ± 10.0 | 48.3 ± 9.5 | 0.77 |
ICU mortality, no. | 4 | 3 | 6 | 2 | 0.84 |
Hospital mortality, no. | 9 | 11 | 7 | 3 | 0.001 |
Values represent mean (SE) in age, BMI, Acute Physiologic Score and Chronic Health Evaluation (APACHE II) score, blood glucose, and Sequential Organ Failure Assessment (SOFA) score on admission to ICU. P-values represent the comparison between diabetic (n = 33) and non-diabetic patients (n = 43). Creatinine clearance = (140 - age(yr))*weight(kg))/(72*serum Cr(mg/dL)) (multiply by 0.85 for women) [34].