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Relationship between the number of measurements and the least significant change of transpulmonary thermodilution variables. CI: cardiac index, GEDVi: global end-diastolic volume indexed for body surface, EVLWi: extravascular lung water indexed for predicted body weight. For instance, for assessing a 15% change in CI, GEDVi or EVLWi with a 95% confidence, one would have to take the mean of three measurements. (Data are expressed as medians and 25 to 75% interquartile ranges).
