Table 7: Double-Blind Placebo-Controlled Treatment Trials of LDLPFC rTMS*.
Study | Effect Size Hedges’d |
Non-Parametric Variance |
Total N |
Frequency in Hz |
Days of Treatment |
Total Daily Stimulation |
Percent Motor Threshold |
---|---|---|---|---|---|---|---|
George et al. 199715 | 1.3691 | 0.3429 | 12 | 20 | 10 | 800 | 80% |
Avery et al. 199616 | 0.7644 | 0.7500 | 6 | 10 | 10 | 1000 | 80% |
Kimbrell et al. 199717 | 0.3188 | 0.2000 | 13 | 1/20 | 10 | 800/800 | 80% |
Loo et al. 19996 | –0.1797 | 0.2222 | 18 | 10 | 10 | 1500 | 110% |
Padberg et al. 199918 | 0.4440 | 0.2500 | 18 | 0.3/10 | 5 | 250/250 | 90% |
Berman et al. 200019 | 1.0504 | 0.2000 | 20 | 20 | 10 | 800 | 80% |
Eschweiler et al. 200020 | 0.2.68 | 0.3429 | 12 | 10 | 10 | 2000 | 90% |
Garcia-Toro et al. 200121 | 1.0783 | 0.1144 | 35 | 20 | 10 | 2000 | 90% |
Garcia-Toro et al. 200122 | 0.1364 | 0.1818 | 22 | 20 | 10 | 1200 | 90% |
George et al. 200023 | 0.6539 | 0.1500 | 30 | 5/20 | 10 | 1600/1600 | 100% |
Lisanby et al. 20017 | 0.2841 | 0.1683 | 24 | 10 | 10 | 1600 | 110% |
Manes et al. 200024 | 0.3003 | 0.2000 | 20 | 20 | 5 | 800 | 80% |
LDLPFC represents left dorsolateral prefrontal cortex; rTMS, repetitive transcranial stimulation. From: Kozel and George (8)