Table 1.
New molecules with H. pylori activity
| Molecule | MIC90 value (mg/L) | pH activity | Cla-R/ Met-R |
|---|---|---|---|
| Arylthiazole derivative 44 | 0.0065 | NA | NA/NA |
| Benzimidazole derivatives | |||
| Y-754 | 0.025 | 5.5 | NA/NA |
| BAS-118 | 0.013 | NA | Yes/yes |
| I-valnemulin | 0.0125–0.5 | NA | Yes/yes |
| Mupirocin | 0.12–0.25 | 5.4 | NA/NA |
| Polycyclic compound | 0.2–0.39 | NA | NA/NA |
| Pyloricidin (A, B, and C) | 0.013 | NA | NA/NA |
| Rifampin | 0.032–2 | NA | Yes/yes |
Notes: MIC90: minimal inhibitory concentration; Cla-R: efficacy towards clarithromycin resistant strains; Met-R: efficacy towards metronidazole resistant strains.
Abbreviation: NA, not available.