Figure 5. Protection of PLG scaffold transplanted islets by ECDI-SP is associated with accumulation of Foxp3+ Treg cells among peri-islet infiltrating cells.
Grafts from days 7, 14 and 21 post transplant were sectioned, stained with Foxp3 antibody and counterstained with hematoxylin. “+tol”: with ECDI-SP infusions; “−tol”: without ECDI-SP infusions. Arrows point to representative Foxp3+ cells. Magnification as indicated.