Table 1.

Characteristics of hyperthermia-induced seizures and neuronal in situ end labeling

Treatment	Hyperthermic seizures (n = 51)	Hyperthermia + AED* (n = 14)	Normothermic controls (n = 24)
Maximal temperature (°C)	42.22  ± 0.07	42.32  ± 0.17	N/A
Seizure duration (min)	19.13  ± 1.21	0 (n = 12); 2; <2	None

Survival time (hr)	1	4	8.5	20*	48
ISEL-labeled cells:
ACE (n)	0  (9)	0.36  ± 0.24 (11)	1.50  ± 0.48 (12)	0.1  ± 0.1 (10)	0.37  ± 0.25 (8)
Hippocampus (n)	0  (9)	0.40  ± 0.21 (11)	1.15  ± 0.32 (13)	0 (10)	0.25  ± 0.25 (8)

ACE, Central nucleus of the amygdala; AED, antiepileptic drug; ISEL, in situ end labeling; N/A, not applicable; (n) denotes number of sections. Animals (marked with *) had hyperthermic seizures twice totaling 60 ± 2 min (see text). Values are means ± SE.