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. Author manuscript; available in PMC: 2012 Jul 2.
Published in final edited form as: Sci Signal. 2011 Jul 12;4(181):rs7. doi: 10.1126/scisignal.2001656

Figure 3. LCI allows direct quantification of the modulation of NICD/RBPjk interactions in live cells.

Figure 3

A. Wild-type (but not WFP>LAA-mutant) RAM polypeptides reduced NΔE-NLuc/CLuc-RBPjκ complementation in a dose-dependent manner. G. MAML-EGFP and dnMAML-EGFP stabilize the interactions between the Notch RAM mutants and RBPjκ. * p<0.01, ** p<0.0001.

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