Table 1.
Mean (SD) of measures of WML burden and their age-corrected partial correlation coefficients and significance levels with overall cortical AChE activity. Burden of frontal lobe WML (natural log transformation of the number of hyperintense voxels) from our reference-based automated method are expressed as percentage of the total white matter volume.
| Frontal periventricular WML Scheltens et al. ratings (27) |
Volume of frontal horn capping (mm3) |
Automated assessment of frontal lobe WML (% hyperintense voxels relative to cerebellum) |
||||
|---|---|---|---|---|---|---|
| Cortical | Mean (SD) | R= −0.517 | Mean (SD) | R= −0.511 | Mean (SD) | R= −0.592 |
| AChE activity |
2.33 (1.28) | P< 0.05 | 0.87 (0.65) | P< 0.05 | 0.67 (0.88) | P< 0.05 |