. 2012 Jul 2;7(7):e39112. doi: 10.1371/journal.pone.0039112

Table 1. Quinacrine concentration (µM) in wild-type and Mdr1 ^0/0 mice.

Tissue	Wild-type	Mdr1 ^0/0	P value
Brain	1.6±0.3	84±2.4	0.0003
Kidney	55±17	138±33	0.01
Liver	207±25	223±50	0.7
Spleen	97±5.3	154±16	0.02

Wild-type and Mdr1^0/0 mice (n = 3) were treated with 40 mg/kg/day of quinacrine in a chocolate-flavored liquid diet for 29 d. After treatment, the mice were euthanized and the quinacrine concentration in each tissue was measured by LC/MS/MS. Values are expressed as the mean ± standard deviation (SD).

Table 1. Quinacrine concentration (µM) in wild-type and Mdr1 0/0 mice.

Table 1. Quinacrine concentration (µM) in wild-type and Mdr1 ^0/0 mice.