Table 2. Pulmonary Function Testing and CT Results of Screened Population.
Pulmonary Function Testing at Enrollment (NHANES) | |
FVC | 3.72L±1.04 |
FVC % pred. | 93.0%±16.6 |
FEV1 | 2.80L±0.83 |
FEV1% pred. | 90.3±18.5 |
FEV1/FVC | 75.0±8.4 |
CT Findings | |
Emphysema on initial CT scan | 420 (35.5%) |
Asbestos-related changes(asbestosis, pleural plaques, and/or pleural thickening) | 171 (14.5%) |
Nodule findings on first or subsequent CTs | |
No nodule | 557 (47.1%) |
Any nodule >4 mm | 625 (52.9%) |
Solid nodules only | 382 (32.4%) |
Sub-solid nodules only | 104 (8.7%) |
Both SN and sub-solid>4 mm | 139 (11.6%) |
Solid Nodules | |
Total individuals with SNs | 519 (45% of total) |
Solitary | 266 (51.3% of SNs) |
Multiple | 253 (48.7% of SNs) |
Total SNs (not individuals) with f/u scans | 1084 |
Resolved on f/u | 105 (9.7% of SNs) |
Mixed pattern | 1 (0.1%) |
Decreased on f/u | 25 (2.3%) |
Increased on f/u | 37 (3.4%) |
Stable on f/u | 916 (84.5%) |
Sub-Solid Nodules | |
Total individuals with sub-solid nodules | 239 (20.3% of total) |
Solitary | 138 (57.9% of SSNs) |
Multiple | |
Total sub-solid nodules with f/u scans | 442 |
Resolved on f/u | 116 (26.2% of SSNs) |
Mixed pattern | 3 (0.7%) |
Decreased on f/u | 40 (9.1%) |
Increased on f/u | 42 (9.5%) |
Stable on f/u | 241 (54.5%) |
Note: many patients had more than one nodule.
Abbreviations: FVC = forced vital capacity, FEV1 = forced expiratory volume in one second, SSN = Sub-solid nodule; SN = solid nodule; f/u = follow up.