Table 4. Characteristics of Prevalent versus Incident Lung Cancers.
Size & CT Densityat Enrollment | Size & CT Densityat Diagnosis | Mean Time Priorto Diagnosis | Histology | Stage at Diagnosis | Median Disease-Free Survival After Diagnosis,& Outcomes | |
All cancers (33) (includes 3 synch. primaries) | 10.8 mm9 SN 14 SSN | 18.6 mm19 SN 14 SSN | 39.8 mths | 26 adeno2 squamous3 small cell2 NSCLC | 26 Stage I2 Stage II4 stage IV | 42 (range 6–113) mths5 expired (lung ca.)4 recurrences (local)1 lost to f/u |
Prevalence cancers dx <6 mths (10) | 19.1 mm7 SN3 SSN | 21.6 mm7 SN3 SSN | 2.4 mths | 9 adeno1 NSCLC | 7 Stage I2 Stage II1 Stage IV | 81.5 (11–113) mths2 expired (lung ca.)1 recurrence (local) |
Prevalence cancers dx >6 mths (13) | 12.8 mm2 SN11 SSN | 20.1 mm7 SN6 SSN | 50.3 mths | 12 adeno1 squamous | 13 stage I | 47 (5–96) mths1 expired (lung ca.)3 recurrences (local)1 expired (cva) |
Incidence cancers (10) | Not presenton initial CT | 13.6 mm5 SN5 SSN | 63.5 mths | 5 adeno1 squamous3 small cell1 NSCLC | 6 stage I3 stage IV | 13 (6–33) mths2 expired (lung ca)1 lost to f/u |
Numbers equal 33 cancers in 30 patients, since three patients had more than one diagnosis of lung cancer (synchronous or second primaries).
Abbreviations: adeno = adenocarcinoma, NSCLC = non-small cell lung cancer not otherwise specified, SN = solid nodule, SSN = sub-solid nodule, ca. = cancer, cva = cerebrovascular accident.