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. 2012 Jul 2;7(7):e39403. doi: 10.1371/journal.pone.0039403

Table 5. Odds Ratios for Risk Factors for the Presence of Nodules on Initial CT Scan*.

Parameter Category OR 95% OR Limit-Lower 95% ORLimit-Upper p-value
All participants Gender (female vs. male) SSN 0.50 0.31 0.80 0.004
Age (older vs. younger) Mixed 1.06 1.04 1.09 <.0001
Emphysema (present vs. absent) SN 1.50 1.10 2.03 0.01
Emphysema (present vs. absent) SSN 1.68 1.05 2.70 0.03
Men Age (older vs. younger) SN 1.03 1.01 1.05 0.011
Age (older vs. younger) Mixed 1.07 1.03 1.10 <.0001
Emphysema (present vs. absent) SN 1.97 1.31 2.95 0.001
Women Age (older vs. younger) Mixed 1.06 1.03 1.09 0.0002
*

Stepwise logistic regression, with OR calculated by gender, presence of emphysema or current age versus 1 year increase in age. For example: OR shows increased age to be a significant risk factor for nodules versus the reference parameter, younger age. Only significant predictors for each category are included.

Abbreviations: SN = solid nodule, SSN = sub-solid nodule.