Figure 5. The relative expression levels of XPF transcripts by the known XPF-rs1799801 genotypes in 270 HapMap subjects.
Homozygous variant CC genotype carriers showed a significant increased trend of XPF mRNA expression levels in overall populations, compare to (A) wild-type TT genotype ones, and (B) recessive reference TT+CT genotype ones (Student’s t test, P = 0.032 and 0.046, respectively); but the difference in XPF transcript expression levels between the variant CC genotype and (C) wild-type TT genotype, and (D) TT+CT genotypes did not reach statistical significance (Student’s t test, P = 0.063 and 0.127, respectively).