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Virus susceptibility to oseltamivir in cell culture
| Virus | IC50 of oseltamivir carboxylatea (nM) |
|---|---|
| A/California/04/2009 (H1N1) (oseltamivir-susceptible control) | 1.4 ± 0.3b |
| A/Osaka/180/2009 (H1N1) (oseltamivir-resistant control) | 1133.5 ± 14.9 |
| H5HA-mutant/pdm09 | 1.0 ± 0.3 |
Oseltamivir carboxylate is the active form of oseltamivir.
IC50 value: mean ± standard deviation from triplicate assays of oseltamivir concentration needed to inhibit neuraminidase activity by 50%.
