Fig. 6.
Comparison of EAAT2 levels in the medial thalamus in pair-fed controls (PFC), TD rats, and in TD rats co-treated with NAC. Results show representative blots of EAAT2 and β-actin along with quantitative analysis in which NAC prevented downregulation of the transporter protein. *P < 0.05 compared with PFC group (one-way ANOVA with posthoc Dunnett's test for multiple comparisons). Photomicrographs show representative cresyl violet staining of medial thalamus from a PFC (A), TD (B), and TD rat co-treated with NAC (C). Note neuronal loss in TD and prevention of this effect following NAC treatment. Bar, 300 lm. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]