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. 2012 Jul;181(1):111–120. doi: 10.1016/j.ajpath.2012.03.026

Figure 1.

Figure 1

Fn14 expression in human NSCLC specimens and correlation with EGFR phosphorylation. A: Fn14 and p-EGFR staining on representative samples from two patients with lung adenocarcinoma (×5 objective, Aperio GL Scanner; Aperio, Vista, CA). Insets: ×40 objective. Tumor cell–specific Fn14 and p-EGFR staining in each of the tumor punches was scored by a board-certified pathologist; a score of 0 indicates a staining level equal to adjacent nontumor cells. A non-0 score indicates increased staining (1, minimum; 2, moderate; 3, strong positive). B: The percentage distribution of staining intensity of Fn14 in NSCLC patient specimens. C: A total of 290 samples were scored for Fn14 and p-EGFR expression, and the correlation between the two stains was analyzed using Kendall's τ rank correlation test.