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. 2012 Jul;181(1):111–120. doi: 10.1016/j.ajpath.2012.03.026

Figure 8.

Figure 8

Fn14 overexpression in NSCLC cells enhances experimental metastases in vivo. A: H&E-stained lung sections from Beige mice with severe combined immunodeficiency, injected i.v. with either control A549 or Fn14-overexpressing A549 cells. Arrows indicate tumors. B: Average number of experimental metastases in lung tumors from mice injected with control A549 or Fn14-overexpressing A549 cells (n = 9 per group). The values shown are the mean ± SEM. Significance was assessed by the Student's t-test. *P < 0.05.